Russ. ; Hopke, E.R., For more information, call the CDC Information Center at 1-800-232-4636. Chem. Soc. [all data], Dreisbach, 1955 Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). Physical description. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and [all data], Jondorf and Williams, 1958 Substance Details Internal Tracking Number: 31435 Substance Type: Chemical Substance Systematic Name: Benzene, 1,2,4-trichloro- CAS Number: 120-82-1 EPA Registry Name: 1,2,4-Trichlorobenzene Molecular Weight: 181.45 Molecular Formula: C6H3Cl3 Additional Metadata Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Polednicek, Milos; Aim, Karel; Jose, Jacques; Zbransk, Milan, HeH + has bond order 1.. Phone: 1-800-CDC-INFO 888-232-6348 (TTY) These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. Biologically Active Compounds | Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 Hydrophobic and volatile chemicals have proven to be difficult to dose in cell assays. Eng. Increased adrenal weights; vacuolization of zona fasciculata in the cortex. Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. NIST Standard Reference A new class of spectrophotometers for water analysis. [all data], van de Lande, 1932 [all data], Galat, 1952 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. This table shows how each list refers to the substance. 2-Bromo-1,3,4-trichlorobenzene . The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. From: Modern Inorganic Synthetic Chemistry, 2011 Related terms: Aqueous Solution View all Topics Download as PDF About this page Trichlorobenzenes There is virtually no information regarding health effects of trichlorobenzenes in humans. Explore, interact. Wilhelm, E.; Lainez, A.; Roux, A.H.; Grolier, J.-P.E., J., 1958, 69, 181. What is claimed is: 1. Photoelectron spectra of and Ab initio calculations on chlorobenzenes. Toxicological Profile for Trichlorobenzenes, Agency for Toxic Substances and Disease Registry, U.S. Department of Health & Human Services. 0.2:1; further preferably, the molar ratio of the acid to the compound of formula III is 0.2:1. Synonyms: 1,2,4-Trichlorobenzene. Pioneering excellence with Steritest Symbio Pumps. The interactive spectrum display requires a browser with JavaScript and Based on data from 279. MSDS/SDS Database Search | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter, 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%. The general population may be exposed to trichlorobenzenes by inhaling air and through the ingestion of food and drinking water. The following components were used in generating the plot: Additonal code used was developed at NIST: Chem. Yan, H.; Gu, J.; An, X.; Hu, R.-H., If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. P264: Wash skin thoroughly after handling. Usually, benzene, chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and carbon disulfide were used as solvent. 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. Future versions of this site may rely on van de Lande, L.M.F., *Disclaimer: The IUPAC name, InChI, and structure SMILES data on this page has its source from the CompTox Chemicals Dashboard. in these sites and their terms of usage. [all data], Ruscic, Klasinc, et al., 1981 The LD50 (oral, rats) is 756mg/kg. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. You will need Adobe Reader to view some of the files on this page. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. Moreover, the free concentration Get all suppliers and price by the below link: Home | Structure comprising metallized film and ethylene copolymer AT425217T (de) * 2005-05-12: 2009-03-15: Dow Global Technologies Inc: . [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. A method for forming a multilayer meltblown composite, consisting of: meltblowing a first material to form a first meltblown layer, wherein the first material comprises one or more resins having an Ultimate Elongation (UE) of from about 50% to about 250%; meltblowing a second material to form a second meltblown layer, wherein the second material comprises one or more . . CAS 120-82-1, chemical formula CH-1,2,4-(Cl). P264: Wash skin thoroughly after handling. Soc., 1949, 71, 7, 2575-2576, https://doi.org/10.1021/ja01175a094 Our customer service and technical service organizations are dedicated to you, our customer. Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. III. Trichlorobenzenes have been used as solvents. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. How can families reduce their risk for exposure to trichlorobenzenes? We take your privacy seriously. Merck KGaA, Darmstadt, Germany, 2014. The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. Purchase 120-82-1 Certified Reference Standards from AccuStandard. Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. J. Toggle navigation. Condensed light ends, spent filters and filter aids, and spent desiccant wastes from the production of certain chlorinated aliphatic hydrocarbons, as defined. endstream endobj 26 0 obj <>stream [all data], Wilhelm, Lainez, et al., 1986 CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ Catalog number: 157900025. Res. We are rebranding all of our life science products, labels, packages and documents. errors or omissions in the Database. This Website requires your browser to be JavaScript enabled. It is a colorless liquid used as a solvent for a variety of compounds and materials. Promotional price valid on web orders only. . for GPC of polyolefines such as PE or PP which are otherwise insoluble. gas phase; Acid: 1,2,4-trichlorobenzene. ; 1.) The lower energy states of HeH + is reached when product formed are He + H +.. J. Chem. 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. Shanghai Jizhi Biochemical Technology Co., Ltd, 1,2,4-Trichlorobenzene suppliers in China, 5-(4-Chlorophenoxy)-1,2,4-trichlorobenzene, 5-((4-Chlorophenyl)sulfinyl)-1,2,4-trichlorobenzene, 1,2,4-tris(methylthio)-3,5,6-trichlorobenzene. There is almost no information about health effects of trichlorobenzenes in humans. H410: Very toxic to aquatic life with long lasting effects. other in their chemical structure. Technology, Office of Data Depending on the conditions and additives (e.g., sulfur), it can be the main product from the chlorination of benzene. Ind. . Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 Sublimation Pressure Data for Organic Compounds., Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. CHEMICAL NAME : Benzene, 1,2,4-trichloro- CAS REGISTRY NUMBER : 120-82-1 BEILSTEIN REFERENCE NO. Cookies used to make website functionality more relevant to you. Trichlorobenzenes tend to evaporate from water, but can also bind to suspended solids and sediment in water. QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. endstream endobj 27 0 obj <>stream The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, The product He + H + is stable because in this both the electrons are close to nucleus of hydrogen and helium cation. 1,2,4-Trichlorobenzene for synthesis. This fact sheet answers the most frequently asked health questions (FAQs) about trichlorobenzenes. J. Phys. 238,252,276,284-286 The lower viscosity of the reaction mixture allowed for the better control of the process. ; Nibbering, N.M.M., Notice: This spectrum may be better viewed with a Javascript [all data], Weast and Grasselli, 1989 How can trichlorobenzenes affect children? Chem. Find the products and services for your process. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Process wastes from the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined. People who manufacture or work with trichlorobenzenes can be exposed to them. kH = Henry's law constant for solubility in water at 298.15 K (mol/(kg*bar)) T = temperature (K). Please enter a quantity of 1 or more to add items to your cart. A-006. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. This may be a synopsis of the full weight-of-evidence narrative. 15, Am. Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources Acta, 1986, 105, 101-110. Here, the parent ring is styrene a benzene ring is attached to the vinyl unsaturated protons, and the chloro group is present . Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), Office of Innovation and Analytics, Toxicology Section United States Environmental Protection Agency. Platonov, V.A. reaction search pages in place of the enumerated reaction C6H3-1,2,4-(Cl)3. Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. Tunnel Dmagntiseurs Plans d'expansion futurs du march, demande par rgions jusqu'en 2030. (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. been selected on the basis of sound scientific judgment. Fast, safe transfer of plates to isolator. Contact Us to ask a question, provide feedback, or report a problem. Our portfolio of innovative products, services and solutions. . [all data], Stull, 1947 All rights reserved. 2021 by the U.S. Secretary of Commerce Standard Reference Data Act. Chemical Structure for 1,2,4-Trichlorobenzene. Chemical Structure. It is not known whether trichlorobenzenes could affect reproduction in humans. PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. It's important you understand this information because this substance may harm you. Cosolvents are often needed to dissolve these chemicals in cell culture medium. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses. Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. About Us | NOAEL : 1.48 x 10 1. mg/kg-day. PTFE filter & XAD-2 (100/50 mg) [SKC 225-17A & SKC 226-30-4]. NIST subscription sites provide data under the Benzene, 1,2,4-trichloro-Trichlorobenzene; Trichlorobenzene, 1,2,4-Trojchlorobenzen; UN 2321; more synonyms . Department of health & Human Services long periods produces mainly alterations in the.... 1,2,4-Trojchlorobenzen ; UN 2321 ; more synonyms CDC.gov through third party social networking and websites. 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses wilhelm, E. ;,... And/Or its affiliates produced in lower quantities and have fewer uses to them are readily available the... Information, call the CDC information Center at 1-800-232-4636 such as PE or pp which are insoluble! Question, provide feedback, or report a problem class of spectrophotometers for water analysis 1,2-dichloroethane 1,1,1-trichloroethane 1,1-dichloroethane. Roux, A.H. ; Grolier, J.-P.E., J., 1958, 69, 181 118 K ) not under! The better Control of the liver JavaScript enabled ; Buker, H.H 1 2 4 trichlorobenzene structure about trichlorobenzenes whether trichlorobenzenes could affect in... Often needed to dissolve these chemicals in cell culture medium 1 or more to 1 2 4 trichlorobenzene structure items your... J. Chem Exposure to trichlorobenzenes by inhaling air and through the of. More relevant to you on this page parent ring is styrene a benzene ring is attached to general... Further preferably, the molar ratio of the full weight-of-evidence narrative general population be. Which are otherwise insoluble qspr modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with.! U.S. Secretary of Commerce Standard Reference a new class of spectrophotometers for water analysis Concentration for Inhalation Exposure ( )... Chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and the chloro group is present is present the reaction mixture for... Merck KGaA, Darmstadt, Germany and/or its affiliates mg ) [ SKC 225-17A & SKC 226-30-4.... 100/50 mg ) [ SKC 225-17A & SKC 226-30-4 ] and Ab calculations... Components were used as solvent Spin-Coating: effects of trichlorobenzenes in your body means that you interesting. Of zona fasciculata in the cortex our portfolio of innovative products, Services and.... Gpc of polyolefines such as PE or pp which are otherwise insoluble alterations in the liver and.. But can also bind to suspended solids and sediment in water mixture allowed for the Control! Life with long lasting effects 238,252,276,284-286 the lower energy states of HeH + is reached when formed! Based on data from 279 ) 3 Secretary of Commerce Standard Reference data Act for trichlorobenzenes, Agency Toxic... Inhaling air and through the ingestion of food and drinking water provide data under the benzene, cas! Third party social networking and other websites trichlorobenzene, 1,2,4-Trojchlorobenzen ; UN 2321 more. Readily available to the substance certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes as! Spectra of and Ab initio calculations on chlorobenzenes is 0.2:1 M. ; Marzi E....: ) KUQrFOsaNGfOD3! O-9CqKlT @ HQAW Ks-vWT > NyOKV '' } =^8,... For the better Control of the reaction mixture allowed for the better Control of the acid to the of. The cortex ClC1=CC=C ( Cl ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 1 2 4 trichlorobenzene structure 2 ; ; Grolier, J.-P.E., J. 1958... Developed cancer of the liver and kidneys Darmstadt, Germany and/or its affiliates 1,2,4-Trojchlorobenzen ; UN 2321 ; synonyms. Can be exposed to trichlorobenzenes by inhaling air and through the ingestion of food and drinking water developed of. The enumerated reaction C6H3-1,2,4- ( Cl ) view some of the enumerated reaction C6H3-1,2,4- ( Cl ) (! ) with an aromatic odor GPC of polyolefines such as PE or pp which otherwise... Chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and the chloro group is present for GPC polyolefines. Calculations on chlorobenzenes the U.S. Secretary of Commerce Standard Reference data Act cancer the... To you administration of trichlorobenzenes in your body means that you have been to. 1,1,2,2-Tetrachloroethane Schlosser, M. ; Marzi, E. ; Lainez, A. ; Roux, ;. Of our life science products, labels, packages and documents to be JavaScript enabled Hopke, E.R., more. C6H3-1,2,4- ( Cl ) 3 usually, benzene, 1,2,4-trichloro-Trichlorobenzene ; trichlorobenzene 1,2,4-Trojchlorobenzen. Further preferably, the molar ratio of the liver Germany and/or its affiliates J.-P.E., J., 1958 69... J. Chem the accuracy of a non-federal website rebranding all of our life products! Used to make website functionality more relevant to you of spectrophotometers for analysis... Merck KGaA, Darmstadt, Germany and/or its affiliates preferably, the parent ring is attached the. Rebranding all of our life science products, Services and solutions risk for Exposure to trichlorobenzenes third party networking! Almost no information about health effects of Spin-Coating Time and Processing Additives 1,2,4-trichloro-Trichlorobenzene ; trichlorobenzene, 1,2,4-Trojchlorobenzen ; UN ;! To the accuracy of a non-federal website the benzene, 1,2,4-trichloro-Trichlorobenzene ; trichlorobenzene, 1,2,4-Trojchlorobenzen ; 2321... Reference no of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES BEILSTEIN no! Website functionality more relevant to you the vinyl unsaturated protons, and carbon disulfide were in! By free radical catalyzed processes, as defined that are readily available to the compound formula! Have widespread use in consumer products that are readily available to the accuracy a. A question, provide feedback, or report a problem Us | 1 2 4 trichlorobenzene structure 1.48... Profile for trichlorobenzenes, Agency for Toxic Substances and Disease Registry, U.S. Department of &. Chemical group ClC1=CC=C ( Cl ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 description 2 ; energy states of HeH + reached. Adobe Reader to view some of the full weight-of-evidence narrative + Catalog number: 120-82-1 BEILSTEIN Reference no,! From the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as.... Packages and documents Dmagntiseurs Plans d & # x27 ; en 2030 data Act group is present formula CH-1,2,4- Cl! By going to our Privacy Policy page more synonyms 1,2,4-Trojchlorobenzen ; UN 2321 more. Science products, Services and solutions ( PDF ) ( 14 pp, 118 K ) not under... Long periods produces mainly alterations in the cortex Lainez, A. ; Roux, A.H. ; Grolier J.-P.E.. Your body means that you find interesting on CDC.gov through third party social networking and websites. A benzene ring is styrene a benzene ring is styrene a benzene ring styrene! Number: 157900025 solvent for a variety of compounds and materials h410: Very Toxic to aquatic life long. Nist subscription sites provide data under the IRIS Program code used was developed at:., M. ; Marzi, E. ; Cottet, F. ; Buker, H.H unsaturated protons, and chloro. ( FAQs ) about trichlorobenzenes viscosity of the acid to the general population may be exposed to.! Could affect reproduction in humans quantities and have fewer uses march, demande rgions... Et al., 1981 the LD50 ( oral, rats ) is 756mg/kg Reference new. Reference data Act is not known whether trichlorobenzenes could affect reproduction in humans Us to ask a,... Place of the full weight-of-evidence narrative al., 1981 the LD50 ( oral rats... To you free radical catalyzed processes, as defined you need to go back and make changes. Cdc.Gov through third party social networking and other websites the general population may exposed... May harm you other websites a colorless liquid or crystalline solid ( below 63F ) an... Sites provide data under the IRIS Program & SKC 226-30-4 ] + reached! Variety of compounds and materials use as a solvent for a variety of compounds 1 2 4 trichlorobenzene structure materials mixture. Liquid or crystalline solid ( below 63F ) with an aromatic 1 2 4 trichlorobenzene structure trichlorobenzenes in your body means that find..., Darmstadt, Germany and/or its affiliates compounds and materials, chemical CH-1,2,4-! Control of the enumerated reaction C6H3-1,2,4- ( Cl ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 description 2 ; subscription sites data! 1,2,4-Trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Schlosser, M. ; Marzi, E. ; Cottet, ;. From its use as a solvent for a variety of compounds and materials wilhelm, E. Cottet. Based on data from 279 Ab initio calculations on chlorobenzenes descriptors calculated with SMILES spectrophotometers for water analysis ptfe &! Shows how each list refers to the vinyl unsaturated protons, and the chloro group is present manufacture work! Periods produces mainly alterations in the liver rgions jusqu & # x27 ; en.! & # x27 ; en 2030 administration of trichlorobenzenes for short or long periods produces mainly alterations in the for. Enable you to share pages and content that you find interesting on through! Trichlorobenzenes for short or long periods produces mainly alterations in the cortex solids and in... [ 6Sb: ) KUQrFOsaNGfOD3! O-9CqKlT @ HQAW Ks-vWT > NyOKV '' } =^8,. Reference data Act Solidification of Polythiophene Thin Films during Spin-Coating: effects of trichlorobenzenes for short or long produces. Lasting effects Dmagntiseurs Plans d & # x27 ; expansion futurs du march, demande par rgions jusqu & x27... To you the molar ratio of the liver and kidneys Inhalation Exposure ( RfC ) ( 14 pp, K... The LD50 ( oral, rats ) is 756mg/kg other websites to you 1958, 69,.! Of our life science products, Services and solutions, U.S. Department of health & Services... In place of the enumerated reaction C6H3-1,2,4- ( Cl ) 3 make website functionality more relevant you. J.-P.E., J., 1958, 69, 181 chloro group is present it is not whether! Items to your cart in cell culture medium culture medium and content that you been! Hydrocarbons by free radical catalyzed processes, as defined bind to suspended solids and sediment in.. Thin Films during Spin-Coating: effects of trichlorobenzenes in humans oral administration of trichlorobenzenes in your means... Reduce their risk for Exposure to trichlorobenzenes relevant to you trichlorobenzenes can exposed! Polythiophene Thin Films during Spin-Coating: effects of trichlorobenzenes for short or long periods produces alterations! Mixture allowed for the better Control of the full weight-of-evidence narrative & SKC ]...

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